Six years after COVID-19’s global alarm: Is the world better prepared for the next pandemic?

<p>Six years ago, the Director-General of the World Health Organization sounded the highest global alarm available under international law at the time, declaring the outbreak of a new coronavirus disease (later known as COVID-19) a Public Health Emergency of International Concern (PHEIC). While the PHEIC was declared over in May 2023, the impact of COVID-19 remains etched in our collective memory &ndash; and continues to be felt worldwide.</p><p>As we cross this six-year mark, WHO asks countries and partners, just as we ask ourselves: Is the world better prepared for the next pandemic?</p><p>The answer is yes and no.</p><p>Yes, in many ways, the world is better prepared because meaningful, concrete steps have been taken to strengthen preparedness. </p><p>However, at the same time, no, because the progress made is fragile and uneven, and more still needs to be done to keep humanity safe.</p><h2>Progress since COVID-19</h2><p>&ldquo;The pandemic taught all of us many lessons &ndash; especially that global threats demand a global response,&rdquo; WHO Director-General Dr Tedros Adhanom Ghebreyesus told today&rsquo;s opening of the 158<sup>th</sup> session of the Executive Board. &ldquo;Solidarity is the best immunity.&rdquo;</p><p>Applying lessons learned from COVID-19, WHO, Member States, and partners have delivered significant advances in pandemic preparedness, prevention and response, including: </p><ul type="disc"><li><strong>the historic WHO Pandemic Agreement was adopted in May 2025</strong>, setting out a truly comprehensive approach to pandemic prevention, preparedness and response that improves both global health security and global health equity.&nbsp; Its conclusion demonstrated the strength of multilateralism. Members States are now negotiating the Pathogen Access and Benefits Sharing (PABS) system annex to the WHO Pandemic Agreement ahead of this year&rsquo;s World Health Assembly. Its adoption would open the Pandemic Agreement for signature, and entry into force as international law;</li><li><strong>amendments to the International Health Regulations (IHR)</strong> to strengthen national capacities entered into force in <strong>September 2025</strong>;</li><li><strong>the Pandemic Fund</strong>, cofounded and implemented by WHO and the World Bank, has provided grant funding totalling <strong>over US$ 1.2 billion</strong> in its first three rounds, which has helped catalyse an additional US$ 11 billion that has so far supported 67 projects in 98 countries across 6 regions, to expand surveillance, lab networks, workforce training and multisectoral coordination; </li><li><strong>WHO&rsquo;s Hub for Pandemic and Epidemic Intelligence</strong> launched a major update of the <strong>Epidemic Intelligence from Open Sources (EIOS)</strong> system, leveraging AI to support more than <strong>110 countries</strong> in identifying and reacting to new threats faster;</li><li><strong>genomic sequencing capacities</strong> globally have surged in recent years and through the <strong>International Pathogen Surveillance Network</strong>, more than <strong>110 countries</strong> have strengthened genomic surveillance to track pathogens with epidemic and pandemic potential and accelerate preparedness and response actions;</li><li>the <strong>WHO BioHub</strong> expanded as a trusted global mechanism, supported by <strong>30 countries and territories</strong>, coordinating <strong>25 sample shipments</strong> to <strong>13 laboratories</strong>. Since launching in late 2020, the BioHub has acquired <strong>34 variants</strong> of the following viruses: SARS-CoV-2; mpox clades Ia, Ib, IIb; the Oropouche virus; and MERS-CoV. Close to 80 laboratories from 30 countries across all WHO regions have engaged in the system by sharing and requesting biological materials;</li><li>global efforts to expand <strong>local, equitable development and production of vaccines, diagnostics and treatments</strong> have accelerated through initiatives including the <strong>mRNA technology transfer hub in Cape Town</strong>, its <strong>training centre in Seoul</strong>, and the <strong>Interim Medical Countermeasures Network</strong>;</li><li><strong>the WHO Academy</strong> in France will help strengthen capacities in countries for pandemic preparedness, including through simulation trainings;</li><li>the <strong>Global Training Hub for Biomanufacturing</strong>, established by the Republic of Korea and WHO, is boosting workforce capacities in manufacturing high-quality vaccines and biologics. By providing training in this critical field, the aim is to increase equitable access to such products globally through expanded manufacturing capacity in low- and middle-income countries;</li><li>the <strong>Global Health Emergency Corps</strong> was set up by WHO in 2023 in response to the gaps and challenges identified during the COVID-19 response. The Corps supports countries experiencing public health emergencies by assessing emergency workforce capacities, rapidly deploying surge support, and creating a network of emergency leaders from multiple countries to share best practices and coordinate responses; and</li><li>the <strong>Universal Health and Preparedness Review (UHPR)</strong> continues to help countries identify gaps and strengthen accountability.</li></ul><p>Other work, which predated the pandemic, continues to strengthen pandemic preparedness, prevention and response: </p><ul type="disc"><li>a hundred and twenty-one countries now have<strong> national public health agencies </strong>responsible for their health emergency prevention, preparedness, response and resilience efforts;<strong> </strong></li><li><strong>twenty countries</strong> completed Joint External Evaluations; <strong>195 States Parties</strong> filed annual IHR reports; <strong>22 countries</strong> finalized National Action Plans for Health Security;</li><li>the <strong>Global Influenza Surveillance and Response System (GISRS)</strong> processes <strong>over 12 million samples</strong> worldwide annually for influenza characterization and to update seasonal influenza vaccines and recommend avian influenza viruses for inter-pandemic production; and</li><li>under the <strong>Pandemic Influenza Preparedness Framework (PIP), </strong>WHO signed eight new agreements in 2025, bringing the total to 19 contracts with pandemic products manufacturers. These agreements have secured access to antivirals, diagnostics, syringes and 900+ million vaccine doses for future influenza pandemics. &nbsp;</li></ul><p>These are <strong>remarkable achievements</strong>, reflecting a shared global commitment to work together across national borders, across sectors to never again face a pandemic unprepared and leave anyone behind. </p><p>WHO Member States have taken decisions that have strengthened the world&rsquo;s ability not only to respond more rapidly and to mitigate the impact of future pandemics but also to prevent them in the first place.</p><p>Recent Ebola and Marburg outbreak responses show this progress clearly at national levels with support from WHO. Ebola, a disease that once had no vaccines, no rapid diagnostics, and limited treatment options &ndash; leading to catastrophic loss of life in West Africa 10 years ago &ndash; has since been transformed. The most recent outbreaks of Ebola in the Democratic Republic of the Congo and Marburg, in Rwanda, Tanzania and Ethiopia, were contained in a fraction of the time, with limited spread and lower case fatality rates. The responses to these outbreaks were led by national institutions, supported by WHO. </p><h2>But these gains are fragile</h2><p>The past years have brought profound turbulence to global health. Funding continues to shift away from health toward defence and national security &ndash; placing at risk the very systems that were strengthened during COVID-19 to protect countries from future pandemics.</p><p>This is shortsighted. <strong>Pandemics <em>are</em> national security threats.</strong></p><p>Investing in preparedness is an investment in:</p><ul type="disc"><li>lives saved</li><li>economies protected</li><li>societies stabilized.</li></ul><h2>A call to action</h2><p>WHO urges all governments, partners and stakeholders: <strong>do not drop the ball on pandemic preparedness and prevention.</strong></p><p>This&nbsp;week&rsquo;s WHO Executive Board meeting will be a pivotal moment in this journey, as governments set the course for designing the future of collaboration,&nbsp;accountability&nbsp;and efficiency in who does what in global health.</p><p>Pathogens don&rsquo;t respect borders. No country can prevent or manage a pandemic alone.</p><p>Global health security requires collaboration across sectors, across governments, and across regions.</p><p>WHO remains committed to working with all countries to strengthen preparedness, accelerate innovation and uphold solidarity. We will continue supporting Member States as they finalize their historic effort to forge a global compact for a world that is safer from pandemics.</p><p><strong>Preparedness requires continuous vigilance. The time to prepare is now &ndash; before the next pandemic strikes.</strong><span style="background-color:transparent;text-align:inherit;text-transform:inherit;word-spacing:normal;caret-color:auto;white-space:inherit;">&nbsp;</span></p><p>&nbsp;</p><p><br /></p>